No subject
Sun Mar 2 20:12:38 EST 2008
"reading a microarray typically requires a high-resolution
digital fluorescence microscope, which is very expensive"
=20
=20
OLPC could be connected to USB chip for fast/cheap diagnostics.
=20
http://www.ece.ualberta.ca/~chrisb/research/lifesciencemain.htm
January 29, 2008
Genetic testing Lab on a chip for less than $100 Canadian <http://nextbig=
future.com/2008/01/genetic-testing-lab-on-chip-for-100.html> =20
Since a journal article was submitted to the Royal Society of Chemistry, =
the U of Alberta researchers have already made the processor and unit sma=
ller and have brought the cost of building a portable unit for genetic te=
sting down to about $100 Cdn. <http://www.eurekalert.org/pub_releases/200=
8-01/uoa-loa012808.php> In addition, these systems are also portable and=
even faster (they take only minutes). Backhouse, Elliott and McMullin ar=
e now demonstrating prototypes of a USB key-like system that may ultimate=
ly be as inexpensive as standard USB memory keys that are in common use -=
only tens of dollars. It could help with Pandemic disease control and de=
tecting and controlling tainted water supplies.
This development fits in with my belief that there should be widespread i=
nexpensive blood, biomarker and genetic tests <http://nextbigfuture.com/2=
007/11/proposal-for-widespread-monitoring-and_09.html> to help catch dis=
ease early and to develop an understanding of biomarker changes to track =
disease and aging development. We can also create adaptive clinical trial=
s to shorten the development and approval process for new medical procedu=
res <http://nextbigfuture.com/2007/12/biomarkers-and-adaptive-clinical-tr=
ials.html>=20
The device is now much smaller than size of a shoe-box (USB stick size) w=
ith the optics and supporting electronics filling the space around the mi=
crochip
Canadian scientists have succeeded in building the least expensive porta=
ble device for rapid genetic testing ever made <http://www.rsc.org/Publis=
hing/ChemScience/Volume/2008/02/Genetic_testing_shoe-box.asp> . The cost =
of carrying out a single genetic test currently varies from hundreds to t=
housands of pounds, and the wait for results can take weeks. Now a group =
led by Christopher Backhouse <http://www.ece.ualberta.ca/~chrisb/> , Univ=
ersity of Alberta, Edmonton, have developed a reusable microchip-based sy=
stem that costs just 500 (pounds) to build, is small enough to be portabl=
e, and can be used for point-of-care medical testing.=20
=09
To keep costs down, 'instead of using the very expensive confocal optics=
systems currently used in these types of devices we used a consumer-grad=
e digital camera', Backhouse explained.=20
=09
The device can be adapted for used in many different genetic tests. 'By =
making small changes to the system you could test for a person's predispo=
sition to cancer, carry out pharmacogenetic tests for adverse drug reacti=
ons or even test for pathogens in a water supply,' said Backhouse.
The heart of the unit, the 'chip,' looks like a standard microscope slid=
e etched with fine silver and gold lines. That microfabricated chip appli=
es nano-biotechnologies within tiny volumes, sometimes working with only =
a few molecules of sample. Because of this highly integrated chip (contai=
ning microfluidics and microscale devices), the remainder of the system i=
s inexpensive ($1,000) and fast.
=09
There are many possible uses for such a portable genetic testing unit:=20=
=09
Backhouse notes that adverse drug reactions are a major problem in healt=
h care. By running a quick genetic test on a cancer patient, for example,=
doctors might pinpoint the type of cancer and determine the best drug an=
d correct dosage for the individual.=20
=09
Or health-care professionals can easily look for the genetic signature f=
or a virus or E. coli - also making it useful for testing water quality.=20=
=09
"From a public health point of view, it would be wonderful during an epi=
demic to be able to do a quick test on a patient when they walk into an e=
mergency room and be able to say, 'you have SARS, you need to go into tha=
t (isolation) room immediately.' "=20
=09
A family doctor might determine a person's genetic predisposition to an =
illness during an office visit and advise the patient on preventative lif=
estyle changes.
Henry Brown
henry.brown at state.nm.us
cell 795-3680
office 505 827-2509
________________________________
From: Brown, Henry, DoIT
Sent: Mon 1/28/2008 11:26 AM
To: Benjamin M. Schwartz
Subject: RE: [OLPC library] 'OLPC-Health' takes off !!- MATLAB for OLPC?
Cheap CMOS CCD technology used in digital cameras may be able replace mic=
roscopes in the near future.
http://www.genewave.com/documents/PS004-03_AmpliReaderW.pdf?PHPSESSID=3D1=
e778bdb95bb62afeb3343f27ff1b428
=20
We need a prototype for clinics in the field. How soon?
There is little economic incentive to develop this technology in developi=
ng markets.
However China and India are developing similar technology to cut health c=
osts.
http://www.sciencedaily.com/releases/2007/03/070330092822.htm
=20
Henry Brown
henry.brown at state.nm.us
cell 795-3680
office 505 827-2509
________________________________
From: Benjamin M. Schwartz [mailto:bmschwar at fas.harvard.edu]
Sent: Mon 1/28/2008 11:00 AM
To: Brown, Henry, DoIT
Cc: Arjun Sarwal; library at lists.laptop.org; devel at lists.laptop.org; ehong=
@mathworks.com; pbaca at sfccnm.edu; acpceo at yahoo.com
Subject: Re: [OLPC library] 'OLPC-Health' takes off !!- MATLAB for OLPC?
On Mon, 2008-01-28 at 08:34 -0700, Brown, Henry, DoIT wrote:
> Could Matlab create Greene Chip DNA microarray software to run on
> OLPC?
> http://www.mailman.hs.columbia.edu/news/Lipkin_GreeneChip.html
> http://www.mathworks.com/matlabcentral/fileexchange/loadFile.do?objectI=
d=3D2573
> http://laptop.org/
> http://www.sciencedaily.com/releases/2008/01/080121100909.htm
>=20
> If the MATLAB software could run on OLPC it could be used to monitor
> disease in the field.
> I worked with AIDS patients and child nutrition programs while in the
> Peace Corps.
> We saw kids die every week from RSV and dehydration caused by
> diarrhea.
> We did not know what antibiotic to give.
> OLPC could use MATLAB software to integrate DNA array results to
> diagnosis.
> An expert system similar to Mycin could then be used to diagnose
> disease in the field via the web.
> http://en.wikipedia.org/wiki/Mycin
Creating new software to read and analyze DNA microarrays is not hard.
MATLAB is not required. If you can make the case for microarray
analysis, appropriate software can be created easily enough.
reading a microarray typically requires a high-resolution
digital fluorescence microscope, which is very expensive
However, . Therefore,
any clinic that can make use of this technology is likely to be able to
afford more appropriate dedicated computing hardware than the XO.
--Ben Schwartz
______________________________________________________________________
This inbound email has been scanned by the MessageLabs Email Security Sys=
tem.
______________________________________________________________________
Confidentiality Notice: This e-mail, including all attachments is for the=
sole use of the intended recipient(s) and may contain confidential and p=
rivileged information. Any unauthorized review, use, disclosure or distri=
bution is prohibited unless specifically provided under the New Mexico In=
spection of Public Records Act. If you are not the intended recipient, pl=
ease contact the sender and destroy all copies of this message. -- This e=
mail has been scanned by the Sybari - Antigen Email System.=20
------_=_NextPart_001_01C88476.2B9FE5CD
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<META HTTP-EQUIV=3D"Content-Type" CONTENT=3D"text/html; charset=3Diso-885=
9-1">=0A=0A=0A<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2//EN">=0A<HTML>=0A=
<HEAD>=0A=0A<META NAME=3D"Generator" CONTENT=3D"MS Exchange Server versio=
n 6.5.7234.20">=0A<TITLE>Re: [OLPC library] 'OLPC-Health' takes off !!- M=
ATLAB for OLPC?</TITLE>=0A</HEAD>=0A<BODY>=0A<DIV id=3DidOWAReplyText8021=
1 dir=3Dltr>=0A<DIV dir=3Dltr><FONT face=3DArial color=3D#000000 size=3D2=
>=0A<DIV id=3DidOWAReplyText18112 dir=3Dltr>=0A<DIV dir=3Dltr><FONT face=3D=
Arial color=3D#000000 size=3D2>=0A<DIV dir=3Dltr><FONT color=3D#000000><E=
M>The Mentor Page: (Want to mentor OLPC/XO =0Acode creation)</EM></FONT><=
/DIV>=0A<DIV dir=3Dltr><FONT color=3D#000000><EM>From slashdot.org:</EM><=
/FONT></DIV>=0A<DIV dir=3Dltr><FONT color=3D#000000><EM>"Just wanted to d=
rop a line reminding open =0Asource projects that they only have until Ma=
rch 12th (Pacific time) to apply for =0A</EM><A href=3D"/exchweb/bin/redi=
r.asp?URL=3Dhttp://code.google.com/soc" =0Atarget=3D_blank><EM>Google's S=
ummer of Code</EM></A><EM>. We are </EM><A =0Ahref=3D"/exchweb/bin/redir.=
asp?URL=3Dhttp://code.google.com/soc/2008/org_signup.html" =0Atarget=3D_b=
lank><EM>accepting more organizations this year</EM></A><EM> than last =0A=
because we want to add a couple hundred more students to the program. If =
you are =0Apart of a great project or know someone who is, we'd love to s=
ee an application. =0APlease note that this is for organizations and not =
for prospective students, =0Athat's not for a few more weeks (see the </E=
M><A =0Ahref=3D"/exchweb/bin/redir.asp?URL=3Dhttp://code.google.com/soc/2=
008/faqs.html%230.1_timeline" =0Atarget=3D_blank><EM>program timeline</EM=
></A><EM>)!"</EM></FONT></DIV>=0A<DIV dir=3Dltr><EM></EM> </DIV>=0A<=
DIV dir=3Dltr><EM><A =0Ahref=3D"/exchweb/bin/redir.asp?URL=3Dhttp://code.=
google.com/soc/2008" =0Atarget=3D_blank>http://code.google.com/soc/2008</=
A></EM></DIV>=0A<DIV dir=3Dltr><A =0Ahref=3D"/exchweb/bin/redir.asp?URL=3D=
http://code.google.com/soc/2008/org_signup.html" =0Atarget=3D_blank>http:=
//code.google.com/soc/2008/org_signup.html</A></DIV>=0A<DIV dir=3Dltr>&nb=
sp;</DIV>=0A<DIV dir=3Dltr>The student page:</DIV></FONT></DIV>=0A<DIV di=
r=3Dltr><FONT face=3DArial color=3D#000000 size=3D2><A =0Ahref=3D"/exchwe=
b/bin/redir.asp?URL=3Dhttp://groups.google.com/group/google-summer-of-cod=
e-announce/web/guide-to-the-gsoc-web-app-for-student-applicants" =0Atarge=
t=3D_blank>http://groups.google.com/group/google-summer-of-code-announce/=
web/guide-to-the-gsoc-web-app-for-student-applicants</A></FONT></DIV>=0A<=
DIV dir=3Dltr> </DIV></DIV></FONT></DIV>=0A<DIV dir=3Dltr><FONT face=
=3DArial color=3D#000000 size=3D2></FONT> </DIV></DIV>=0A<DIV id=3Di=
dSignature50601 dir=3Dltr>=0A<DIV><FONT face=3DArial color=3D#000000 size=
=3D2>Henry Brown</FONT></DIV>=0A<DIV><FONT face=3DArial size=3D2><A =0Ahr=
ef=3D"mailto:henry.brown at state.nm.us">henry.brown at state.nm.us</FONT><FONT=
=0Aface=3DArial size=3D2><SPAN =0Astyle=3D"FONT-SIZE: 10pt; FONT-FAMILY:=
Arial"></SPAN></FONT></A></DIV>=0A<DIV><FONT face=3DArial size=3D2><SPAN=
=0Astyle=3D"FONT-SIZE: 10pt; FONT-FAMILY: Arial">cell 795-3680</SPAN></F=
ONT></DIV>=0A<DIV><FONT face=3DArial size=3D2><SPAN =0Astyle=3D"FONT-SIZE=
: 10pt; FONT-FAMILY: Arial">office </SPAN></FONT><FONT =0Aface=3DArial si=
ze=3D2>505 827-2509</FONT></DIV></DIV>=0A<DIV dir=3Dltr><BR>=0A<HR tabInd=
ex=3D-1>=0A<FONT face=3DTahoma size=3D2><B>From:</B> Brown, Henry, DoIT<B=
R><B>Sent:</B> Thu =0A1/31/2008 2:46 PM<BR><B>To:</B> Brown, Henry, DoIT;=
Benjamin M. =0ASchwartz<BR><B>Cc:</B> library at lists.laptop.org; =0Adevel=
@lists.laptop.org<BR><B>Subject:</B> OLPC Tricoder for field =0Adoctors<B=
R></FONT><BR></DIV>=0A<DIV>=0A<DIV id=3DidOWAReplyText89570 dir=3Dltr>=0A=
<DIV dir=3Dltr><FONT color=3D#000000 size=3D2>From Ben Schwartz:</FONT></=
DIV>=0A<DIV dir=3Dltr><FONT color=3D#000000 size=3D2>"reading a microarra=
y typically requires =0Aa high-resolution<BR>digital fluorescence microsc=
ope, which is very =0Aexpensive"</FONT></DIV>=0A<DIV dir=3Dltr><FONT size=
=3D2></FONT> </DIV>=0A<DIV dir=3Dltr><FONT size=3D2></FONT> </D=
IV>=0A<DIV dir=3Dltr><FONT face=3DArial color=3D#000000 size=3D2>OLPC cou=
ld be connected to =0AUSB chip for fast/cheap diagnostics.</FONT></DIV>=0A=
<DIV dir=3Dltr><FONT face=3DArial size=3D2></FONT> </DIV>=0A<DIV dir=
=3Dltr><FONT face=3DArial color=3D#000000 size=3D2><A =0Ahref=3D"http://w=
ww.ece.ualberta.ca/~chrisb/research/lifesciencemain.htm">http://www.ece.u=
alberta.ca/~chrisb/research/lifesciencemain.htm</A></FONT></DIV>=0A<DIV d=
ir=3Dltr><FONT face=3DArial color=3D#000000 size=3D2>January 29, 200=
8</DIV>=0A<DIV class=3D"post hentry" id=3Dpost-1269809166970516592 dir=3D=
ltr><A =0Aname=3D1269809166970516592></A>=0A<H3 class=3D"post-title entry=
-title"><A =0Ahref=3D"http://nextbigfuture.com/2008/01/genetic-testing-la=
b-on-chip-for-100.html">Genetic =0Atesting Lab on a chip for less than $1=
00 Canadian</A> </H3>=0A<DIV class=3Dpost-header-line-1></DIV>=0A<DIV cla=
ss=3D"post-body entry-content">=0A<STYLE>#fullpost {display:none;}</STYLE=
>=0A=0A<P><A href=3D"http://www.eurekalert.org/pub_releases/2008-01/uoa-l=
oa012808.php" =0Atarget=3Dblank><FONT color=3D#5588aa>Since a journal art=
icle was submitted to the =0ARoyal Society of Chemistry, the U of Alberta=
researchers have already made the =0Aprocessor and unit smaller and have=
brought the cost of building <STRONG>a =0Aportable unit for genetic test=
ing</STRONG> <STRONG>down to about $100 =0ACdn</STRONG>.</FONT></A> In ad=
dition, these systems are also portable and even =0Afaster (they take onl=
y minutes). Backhouse, Elliott and McMullin are <STRONG>now =0Ademonstrat=
ing prototypes of a USB key-like system </STRONG>that may ultimately =0Ab=
e as inexpensive as standard USB memory keys that are in common use ̵=
1; =0A<STRONG>only tens of dollars</STRONG>. It could help with Pandemic =
disease =0Acontrol and detecting and controlling tainted water supplies.<=
BR><BR>This =0Adevelopment fits in with my belief that there should be <A=
=0Ahref=3D"http://nextbigfuture.com/2007/11/proposal-for-widespread-moni=
toring-and_09.html" =0Atarget=3Dblank><FONT color=3D#5588aa>widespread in=
expensive blood, biomarker and =0Agenetic tests</FONT></A> to help catch =
disease early and to develop an =0Aunderstanding of biomarker changes to =
track disease and aging development. <A =0Ahref=3D"http://nextbigfuture.c=
om/2007/12/biomarkers-and-adaptive-clinical-trials.html" =0Atarget=3Dblan=
k><FONT color=3D#5588aa>We can also create adaptive clinical trials to =0A=
shorten the development and approval process for new medical =0Aprocedure=
s</FONT></A><BR><BR><FONT color=3D#5588aa><IMG src=3D""><BR></FONT>The =0A=
device is now much smaller than size of a shoe-box (USB stick size) with =
the =0Aoptics and supporting electronics filling the space around the mic=
rochip<BR><BR>=0A<BLOCKQUOTE>Canadian scientists have <A =0A href=3D"htt=
p://www.rsc.org/Publishing/ChemScience/Volume/2008/02/Genetic_testing_sho=
e-box.asp" =0A target=3Dblank><FONT color=3D#5588aa>succeeded in buildin=
g the least expensive =0A portable device for rapid genetic testing ever=
made</FONT></A>. The cost of =0A carrying out a single genetic test cur=
rently varies from hundreds to thousands =0A of pounds, and the wait for=
results can take weeks. Now a group led by <A =0A href=3D"http://www.ec=
e.ualberta.ca/~chrisb/" target=3Dblank><FONT =0A color=3D#5588aa>Christo=
pher Backhouse</FONT></A>, University of Alberta, =0A Edmonton, have dev=
eloped a reusable microchip-based system that costs just 500 =0A (pounds=
) to build, is small enough to be portable, and can be used for =0A poin=
t-of-care medical testing. <BR><BR>To keep costs down, 'instead of using =
=0A the very expensive confocal optics systems currently used in these t=
ypes of =0A devices we used a consumer-grade digital camera', Backhouse =
explained. =0A <BR><BR>The device can be adapted for used in many differ=
ent genetic tests. =0A 'By making small changes to the system you could =
test for a person's =0A predisposition to cancer, carry out pharmacogene=
tic tests for adverse drug =0A reactions or even test for pathogens in a=
water supply,' said =0ABackhouse.</BLOCKQUOTE></DIV></DIV></FONT>=0A<DIV=
dir=3Dltr><FONT face=3DArial color=3D#000000 size=3D2>=0A<BLOCKQUOTE>The=
heart of the unit, the ‘chip,’ looks like a standard =0A mi=
croscope slide etched with fine silver and gold lines. That microfabricat=
ed =0A chip applies nano-biotechnologies within tiny volumes, sometimes =
working with =0A only a few molecules of sample. Because of this highly =
integrated chip =0A (containing microfluidics and microscale devices), t=
he remainder of the system =0A is inexpensive ($1,000) and fast.<BR><BR>=
There are many possible uses for such =0A a portable genetic testing uni=
t: <BR><BR>Backhouse notes that adverse drug =0A reactions are a major p=
roblem in health care. By running a quick genetic test =0A on a cancer p=
atient, for example, doctors might pinpoint the type of cancer =0A and d=
etermine the best drug and correct dosage for the individual. <BR><BR>Or =
=0A health-care professionals can easily look for the genetic signature =
for a =0A virus or E. coli – also making it useful for testing wat=
er quality. =0A <BR><BR>“From a public health point of view, it wo=
uld be wonderful during an =0A epidemic to be able to do a quick test on=
a patient when they walk into an =0A emergency room and be able to say,=
‘you have SARS, you need to go into that =0A (isolation) room imm=
ediately.’ ” <BR><BR>A family doctor might determine a =0A p=
erson’s genetic predisposition to an illness during an office visit=
and =0A advise the patient on preventative lifestyle =0Achanges.</BLOCK=
QUOTE><BR></FONT></DIV></DIV>=0A<DIV id=3DidSignature23991 dir=3Dltr>=0A<=
DIV><FONT face=3DArial color=3D#000000 size=3D2>Henry Brown</FONT></DIV>=0A=
<DIV><FONT face=3DArial size=3D2><A =0Ahref=3D"mailto:henry.brown at state.n=
m.us">henry.brown at state.nm.us</FONT><FONT =0Aface=3DArial size=3D2><SPAN =
=0Astyle=3D"FONT-SIZE: 10pt; FONT-FAMILY: Arial"></SPAN></FONT></A></DIV>=
=0A<DIV><FONT face=3DArial size=3D2><SPAN =0Astyle=3D"FONT-SIZE: 10pt; FO=
NT-FAMILY: Arial">cell 795-3680</SPAN></FONT></DIV>=0A<DIV><FONT face=3DA=
rial size=3D2><SPAN =0Astyle=3D"FONT-SIZE: 10pt; FONT-FAMILY: Arial">offi=
ce </SPAN></FONT><FONT =0Aface=3DArial size=3D2>505 827-2509</FONT></DIV>=
</DIV>=0A<DIV dir=3Dltr><BR>=0A<HR tabIndex=3D-1>=0A<FONT face=3DTahoma s=
ize=3D2><B>From:</B> Brown, Henry, DoIT<BR><B>Sent:</B> Mon =0A1/28/2008 =
11:26 AM<BR><B>To:</B> Benjamin M. Schwartz<BR><B>Subject:</B> RE: =0A[OL=
PC library] 'OLPC-Health' takes off !!- MATLAB for OLPC?<BR></FONT><BR></=
DIV>=0A<DIV>=0A<DIV id=3DidOWAReplyText86201 dir=3Dltr>=0A<DIV dir=3Dltr>=
<FONT face=3DArial color=3D#000000 size=3D2>Cheap CMOS CCD technology =0A=
used in digital cameras may be able replace microscopes in the near =
=0Afuture.</FONT></DIV>=0A<DIV dir=3Dltr><FONT face=3DArial size=3D2><A =0A=
href=3D"http://www.genewave.com/documents/PS004-03_AmpliReaderW.pdf?PHPSE=
SSID=3D1e778bdb95bb62afeb3343f27ff1b428">http://www.genewave.com/document=
s/PS004-03_AmpliReaderW.pdf?PHPSESSID=3D1e778bdb95bb62afeb3343f27ff1b428<=
/A></FONT></DIV>=0A<DIV dir=3Dltr><FONT face=3DArial size=3D2></FONT>&nbs=
p;</DIV>=0A<DIV dir=3Dltr><FONT face=3DArial size=3D2>We need a prototype=
for clinics in the =0Afield. How soon?</FONT></DIV>=0A<DIV dir=3Dltr><FO=
NT face=3DArial size=3D2>There is little economic incentive to =0Adevelop=
this technology in developing markets.</FONT></DIV>=0A<DIV dir=3Dltr><FO=
NT face=3DArial size=3D2>However China and India are developing =0Asimila=
r technology to cut health costs.</FONT></DIV>=0A<DIV dir=3Dltr><A =0Ahre=
f=3D"http://www.sciencedaily.com/releases/2007/03/070330092822.htm">http:=
//www.sciencedaily.com/releases/2007/03/070330092822.htm</A></DIV>=0A<DIV=
dir=3Dltr><FONT face=3DArial color=3D#000000 size=3D2></FONT> </DIV=
></DIV>=0A<DIV id=3DidSignature17869 dir=3Dltr>=0A<DIV><FONT face=3DArial=
color=3D#000000 size=3D2>Henry Brown</FONT></DIV>=0A<DIV><FONT face=3DAr=
ial size=3D2><A =0Ahref=3D"mailto:henry.brown at state.nm.us">henry.brown at st=
ate.nm.us</FONT><FONT =0Aface=3DArial size=3D2><SPAN =0Astyle=3D"FONT-SIZ=
E: 10pt; FONT-FAMILY: Arial"></SPAN></FONT></A></DIV>=0A<DIV><FONT face=3D=
Arial size=3D2><SPAN =0Astyle=3D"FONT-SIZE: 10pt; FONT-FAMILY: Arial">cel=
l 795-3680</SPAN></FONT></DIV>=0A<DIV><FONT face=3DArial size=3D2><SPAN =0A=
style=3D"FONT-SIZE: 10pt; FONT-FAMILY: Arial">office </SPAN></FONT><FONT =
=0Aface=3DArial size=3D2>505 827-2509</FONT></DIV></DIV>=0A<DIV dir=3Dltr=
><BR>=0A<HR tabIndex=3D-1>=0A<FONT face=3DTahoma size=3D2><B>From:</B> Be=
njamin M. Schwartz =0A[mailto:bmschwar at fas.harvard.edu]<BR><B>Sent:</B> M=
on 1/28/2008 11:00 =0AAM<BR><B>To:</B> Brown, Henry, DoIT<BR><B>Cc:</B> A=
rjun Sarwal; =0Alibrary at lists.laptop.org; devel at lists.laptop.org; ehong at m=
athworks.com; =0Apbaca at sfccnm.edu; acpceo at yahoo.com<BR><B>Subject:</B> Re=
: [OLPC library] =0A'OLPC-Health' takes off !!- MATLAB for OLPC?<BR></FON=
T><BR></DIV>=0A<DIV>=0A<P><FONT size=3D2>On Mon, 2008-01-28 at 08:34 -070=
0, Brown, Henry, DoIT =0Awrote:<BR><BR>> Could Matlab create Greene Ch=
ip DNA microarray software to =0Arun on<BR>> OLPC?<BR>> <A =0Ahref=3D=
"http://www.mailman.hs.columbia.edu/news/Lipkin_GreeneChip.html">http://w=
ww.mailman.hs.columbia.edu/news/Lipkin_GreeneChip.html</A><BR>> =0A<A =
=0Ahref=3D"http://www.mathworks.com/matlabcentral/fileexchange/loadFile.d=
o?objectId=3D2573">http://www.mathworks.com/matlabcentral/fileexchange/lo=
adFile.do?objectId=3D2573</A><BR>> =0A<A href=3D"http://laptop.org/">h=
ttp://laptop.org/</A><BR>> <A =0Ahref=3D"http://www.sciencedaily.com/r=
eleases/2008/01/080121100909.htm">http://www.sciencedaily.com/releases/20=
08/01/080121100909.htm</A><BR>> <BR>> =0AIf the MATLAB softwar=
e could run on OLPC it could be used to monitor<BR>> =0Adisease in the=
field.<BR>> I worked with AIDS patients and child nutrition =0Aprogra=
ms while in the<BR>> Peace Corps.<BR>> We saw kids die every week =0A=
from RSV and dehydration caused by<BR>> diarrhea.<BR>> We did not k=
now =0Awhat antibiotic to give.<BR>> OLPC could use MATLAB software to=
integrate DNA =0Aarray results to<BR>> diagnosis.<BR>> An expert s=
ystem similar to Mycin =0Acould then be used to diagnose<BR>> disease =
in the field via the web.<BR>> =0A<A =0Ahref=3D"http://en.wikipedia.or=
g/wiki/Mycin">http://en.wikipedia.org/wiki/Mycin</A><BR><BR>Creating =0An=
ew software to read and analyze DNA microarrays is not hard.<BR>MATLAB is=
not =0Arequired. If you can make the case for microarray<BR>analys=
is, appropriate =0Asoftware can be created easily enough.<BR>reading a mi=
croarray typically =0Arequires a high-resolution<BR>digital fluorescence =
microscope, which is very =0Aexpensive<BR>However, . Therefore,<BR>=
any clinic that can make use of this =0Atechnology is likely to be able t=
o<BR>afford more appropriate dedicated =0Acomputing hardware than the XO.=
<BR><BR>--Ben =0ASchwartz<BR><BR><BR><BR>________________________________=
______________________________________<BR>This =0Ainbound email has been =
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